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YY1 is a ubiquitously distributed transcription factor belonging to the GLI Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expr

This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocy

抗體定制服務(wù)$nBioss免疫學(xué)相關(guān)實(shí)驗(yàn)服務(wù)，實(shí)驗(yàn)成功率高，服務(wù)周期短，并有經(jīng)驗(yàn)豐富的免疫學(xué)技術(shù)人員為您提供技術(shù)支持，可為您完成從蛋白表達(dá)到抗體制備，再到免疫學(xué)檢測的整個(gè)流程實(shí)驗(yàn)。

FITC標(biāo)記的細(xì)胞間粘附分子-1抗體 CD54（ICAM-1）是分子量為60-110KD的膜型糖蛋白，表達(dá)于單核和內(nèi)皮細(xì)胞。許多細(xì)胞如B或T淋巴細(xì)胞、胸腺細(xì)胞、纖維母細(xì)胞和上皮細(xì)胞都可誘導(dǎo)表達(dá)CD54，在調(diào)節(jié)免疫和炎癥反應(yīng)中CD54有重要作用。